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Characterization of an Isotype-Dependent Monoclonal Antibody against Linear Neutralizing Epitope Effective for Prophylaxis of Enterovirus 71 Infection

BACKGROUND: Enterovirus 71 (EV71) is the main causative agent of Hand, Foot and Mouth disease (HFMD) and is associated with severe neurologic complications and mortalities. At present, there is no vaccine or therapeutic available for treatment. METHODOLOGY/PRINCIPAL FINDING: In this study, we genera...

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書誌詳細
主要な著者: Lim, Xiao Fang, Jia, Qiang, Khong, Wei Xin, Yan, Benedict, Premanand, Balraj, Alonso, Sylvie, Chow, Vincent T. K., Kwang, Jimmy
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3261156/
https://ncbi.nlm.nih.gov/pubmed/22279543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0029751
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