Characterization of an Isotype-Dependent Monoclonal Antibody against Linear Neutralizing Epitope Effective for Prophylaxis of Enterovirus 71 Infection

BACKGROUND: Enterovirus 71 (EV71) is the main causative agent of Hand, Foot and Mouth disease (HFMD) and is associated with severe neurologic complications and mortalities. At present, there is no vaccine or therapeutic available for treatment. METHODOLOGY/PRINCIPAL FINDING: In this study, we genera...

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Detalhes bibliográficos
Main Authors: Lim, Xiao Fang, Jia, Qiang, Khong, Wei Xin, Yan, Benedict, Premanand, Balraj, Alonso, Sylvie, Chow, Vincent T. K., Kwang, Jimmy
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3261156/
https://ncbi.nlm.nih.gov/pubmed/22279543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0029751
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