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HPLC separation of human serum albumin isoforms based on their isoelectric points
Human serum albumin (HSA) is the most abundant protein in plasma. Cys34, the only free Cys residue, is the predominant plasma thiol and a relevant sacrificial antioxidant. Both in vivo circulating HSA and pharmaceutical preparations are heterogeneous with respect to the oxidation state of Cys34. In...
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| Hauptverfasser: | , , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4038395/ https://ncbi.nlm.nih.gov/pubmed/24316526 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jchromb.2013.11.019 |
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