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Modulation of the reactivity of the thiol of human serum albumin and its sulfenic derivative by fatty acids

The single cysteine residue of human serum albumin (HSA-SH) is the most abundant plasma thiol. HSA transports fatty acids (FA), a cargo that increases under conditions of diabetes, exercise or adrenergic stimulation. The stearic acid-HSA (5/1) complex reacted 6-fold faster at pH 7.4 with the disulfi...

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Detalhes bibliográficos
Main Authors: Torres, María José, Turell, Lucía, Botti, Horacio, Antmann, Laura, Carballal, Sebastián, Ferrer-Sueta, Gerardo, Radi, Rafael, Alvarez, Beatriz
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3345106/
https://ncbi.nlm.nih.gov/pubmed/22450170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2012.03.011
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