Regulated Splicing of the α6 Integrin Cytoplasmic Domain Determines the Fate of Breast Cancer Stem Cells

Although the α6β1 integrin has been implicated in the function of breast and other cancer stem cells (CSCs), little is known about its regulation and relationship to mechanisms involved in the genesis of CSCs. We report that a CD44(high)/CD24(low) population, enriched for CSCs, is comprised of disti...

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Autori principali: Goel, Hira Lal, Gritsko, Tatiana, Pursell, Bryan, Chang, Cheng, Shultz, Leonard D., Greiner, Dale L., Norum, Jens Henrik, Toftgard, Rune, Shaw, Leslie M., Mercurio, Arthur M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4038359/
https://ncbi.nlm.nih.gov/pubmed/24767994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2014.03.059
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