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Regulated Splicing of the α6 Integrin Cytoplasmic Domain Determines the Fate of Breast Cancer Stem Cells

Although the α6β1 integrin has been implicated in the function of breast and other cancer stem cells (CSCs), little is known about its regulation and relationship to mechanisms involved in the genesis of CSCs. We report that a CD44(high)/CD24(low) population, enriched for CSCs, is comprised of disti...

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Detalhes bibliográficos
Main Authors: Goel, Hira Lal, Gritsko, Tatiana, Pursell, Bryan, Chang, Cheng, Shultz, Leonard D., Greiner, Dale L., Norum, Jens Henrik, Toftgard, Rune, Shaw, Leslie M., Mercurio, Arthur M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4038359/
https://ncbi.nlm.nih.gov/pubmed/24767994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2014.03.059
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