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Effect of C-terminal Sequence on Competitive Semaphorin Binding to Neuropilin-1

Neuropilins (Nrp) are type I transmembrane proteins that function as receptors for Vascular Endothelial Growth Factor (VEGF) and class III Semaphorin (Sema3) ligand families. Sema3s function as potent endogenous angiogenesis inhibitors, but require proteolytically processing by furin to compete with...

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Détails bibliographiques
Auteurs principaux: Parker, Matthew W., Linkugel, Andrew D., Vander Kooi, Craig W.
Format: Artigo
Langue:Inglês
Publié: 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4038064/
https://ncbi.nlm.nih.gov/pubmed/23871893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2013.07.017
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