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Furin Processing of Semaphorin 3F Determines its Anti-Angiogenic Activity by Regulating Direct Binding and Competition for Neuropilin

Neuropilin is an essential cell surface receptor that functions in both semaphorin dependent axon guidance and vascular endothelial growth factor (VEGF) dependent angiogenesis. The interplay between these two seemingly distinct pathways is a source of considerable interest. Indeed, several semaphori...

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Hlavní autoři: Parker, Matthew W., Hellman, Lance M., Xu, Ping, Fried, Michael G., Kooi, Craig W. Vander
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2868107/
https://ncbi.nlm.nih.gov/pubmed/20387901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi100327r
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