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Mechanistic Basis for the Potent Anti-angiogenic Activity of Semaphorin 3F
Neuropilin-1 (Nrp1), an essential type I transmembrane receptor, binds two secreted ligand families, Vascular Endothelial Growth Factor (VEGF) and class III Semaphorin (Sema3). VEGF-A and Sema3F have opposing roles in regulating Nrp1 vascular function in angiogenesis. VEGF-A functions as one of the...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2013
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3873856/ https://ncbi.nlm.nih.gov/pubmed/24079887 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi401034q |
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