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Importance of Input Perturbations and Stochastic Gene Expression in the Reverse Engineering of Genetic Regulatory Networks: Insights From an Identifiability Analysis of an In Silico Network

Gene expression profiles are an increasingly common data source that can yield insights into the functions of cells at a system-wide level. The present work considers the limitations in information content of gene expression data for reverse engineering regulatory networks. An in silico genetic regu...

詳細記述

保存先:
書誌詳細
出版年:Genome Res
主要な著者: Zak, Daniel E., Gonye, Gregory E., Schwaber, James S., Doyle, Francis J.
フォーマット: Artigo
言語:Inglês
出版事項: Cold Spring Harbor Laboratory Press 2003
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC403758/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14597654/
https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gr.1198103
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