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Reverse engineering gene networks: Integrating genetic perturbations with dynamical modeling

While the fundamental building blocks of biology are being tabulated by the various genome projects, microarray technology is setting the stage for the task of deducing the connectivity of large-scale gene networks. We show how the perturbation of carefully chosen genes in a microarray experiment ca...

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Detalhes bibliográficos
Main Authors: Tegnér, Jesper, Yeung, M. K. Stephen, Hasty, Jeff, Collins, James J.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC156306/
https://ncbi.nlm.nih.gov/pubmed/12730377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0933416100
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