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Improved Reconstruction of In Silico Gene Regulatory Networks by Integrating Knockout and Perturbation Data

We performed computational reconstruction of the in silico gene regulatory networks in the DREAM3 Challenges. Our task was to learn the networks from two types of data, namely gene expression profiles in deletion strains (the ‘deletion data’) and time series trajectories of gene expression after som...

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書誌詳細
主要な著者: Yip, Kevin Y., Alexander, Roger P., Yan, Koon-Kiu, Gerstein, Mark
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2811182/
https://ncbi.nlm.nih.gov/pubmed/20126643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0008121
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