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Improved Reconstruction of In Silico Gene Regulatory Networks by Integrating Knockout and Perturbation Data

We performed computational reconstruction of the in silico gene regulatory networks in the DREAM3 Challenges. Our task was to learn the networks from two types of data, namely gene expression profiles in deletion strains (the ‘deletion data’) and time series trajectories of gene expression after som...

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Autori principali: Yip, Kevin Y., Alexander, Roger P., Yan, Koon-Kiu, Gerstein, Mark
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2811182/
https://ncbi.nlm.nih.gov/pubmed/20126643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0008121
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