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Comparing genomes to computer operating systems in terms of the topology and evolution of their regulatory control networks

The genome has often been called the operating system (OS) for a living organism. A computer OS is described by a regulatory control network termed the call graph, which is analogous to the transcriptional regulatory network in a cell. To apply our firsthand knowledge of the architecture of software...

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Bibliographic Details
Main Authors: Yan, Koon-Kiu, Fang, Gang, Bhardwaj, Nitin, Alexander, Roger P., Gerstein, Mark
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2889091/
https://ncbi.nlm.nih.gov/pubmed/20439753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0914771107
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