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Perilous journey: a tour of the ubiquitin–proteasome system

Eukaryotic cells are equipped to degrade proteins via the ubiquitin–proteasome system (UPS). Proteins become degraded upon their conjugation to chains of ubiquitin where they are then directed to the 26S proteasome, a macromolecular protease. The transfer of ubiquitin to proteins and their subsequen...

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Detalhes bibliográficos
Main Authors: Kleiger, Gary, Mayor, Thibault
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4037451/
https://ncbi.nlm.nih.gov/pubmed/24457024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tcb.2013.12.003
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