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How the ubiquitin proteasome system regulates the regulators of transcription

The ubiquitin proteasome system plays an important role in transcription. Monoubiquitination of activators is believed to aid their function, while the 26S proteasomal degradation of repressors is believed to restrict their function. What remains controversial is the question of whether the degradat...

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Detalhes bibliográficos
Main Authors: Ee, Gary, Lehming, Norbert
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3632619/
https://ncbi.nlm.nih.gov/pubmed/22885980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/trns.21249
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