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Erythropoiesis from Human Embryonic Stem Cells Through Erythropoietin-Independent AKT Signaling

Unlimited self renewal capacity and differentiation potential make human pluripotent stem cells (PSC) a promising source for the ex vivo manufacture of red blood cells (RBC) for safe transfusion. Current methods to induce erythropoiesis from PSC suffer from low yields of RBCs, most of which are imma...

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Detalhes bibliográficos
Main Authors: Kim, William S., Zhu, Yuhua, Deng, Qiming, Chin, Chee Jia, He, Chong Bin, Grieco, Amanda J., Dravid, Gautam G., Parekh, Chintan, Hollis, Roger P., Lane, Timothy F., Bouhassira, Eric E., Kohn, Donald B., Crooks, Gay M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4037366/
https://ncbi.nlm.nih.gov/pubmed/24677652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.1677
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