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Extensive Exon Reshuffling Over Evolutionary Time Coupled to Trans-Splicing in Drosophila
The relative position of exons in genes can be altered only after large structural mutations. These mutations are frequently deleterious, impairing transcription, splicing, RNA stability, or protein function, as well as imposing strong inflexibility to protein evolution. Alternative cis- or trans-sp...
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Main Authors: | , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Cold Spring Harbor Laboratory Press
2003
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC403680/ https://ncbi.nlm.nih.gov/pubmed/14525924 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.1440703 |
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