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Extensive Exon Reshuffling Over Evolutionary Time Coupled to Trans-Splicing in Drosophila

The relative position of exons in genes can be altered only after large structural mutations. These mutations are frequently deleterious, impairing transcription, splicing, RNA stability, or protein function, as well as imposing strong inflexibility to protein evolution. Alternative cis- or trans-sp...

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Detalhes bibliográficos
Main Authors: Labrador, Mariano, Corces, Victor G.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC403680/
https://ncbi.nlm.nih.gov/pubmed/14525924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.1440703
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