Switching and emergence of CTL epitopes in HIV-1 infection

BACKGROUND: Human Leukocyte Antigen (HLA) class I restricted Cytotoxic T Lymphocytes (CTLs) exert substantial evolutionary pressure on HIV-1, as evidenced by the reproducible selection of HLA-restricted immune escape mutations in the viral genome. An escape mutation from tyrosine to phenylalanine at...

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Autores principales: Han, Chungyong, Kawana-Tachikawa, Ai, Shimizu, Akihisa, Zhu, Dayong, Nakamura, Hitomi, Adachi, Eisuke, Kikuchi, Tadashi, Koga, Michiko, Koibuchi, Tomohiko, Gao, George F, Sato, Yusuke, Yamagata, Atsushi, Martin, Eric, Fukai, Shuya, Brumme, Zabrina L, Iwamoto, Aikichi
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4036671/
https://ncbi.nlm.nih.gov/pubmed/24886641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-11-38
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