Rapid HIV-1 Disease Progression in Individuals Infected with a Virus Adapted to Its Host Population

HIV-1 escape from CTL is predictable based on the Human Leukocyte Antigen (HLA) class I alleles expressed by the host. As such, HIV-1 sequences circulating in a population of hosts will harbor escape mutations specific to the HLA alleles of that population. In theory, this should increase the freque...

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Udgivet i:PLoS One
Main Authors: Katoh, Jiro, Kawana-Tachikawa, Ai, Shimizu, Akihisa, Zhu, Dayong, Han, Chungyong, Nakamura, Hitomi, Koga, Michiko, Kikuchi, Tadashi, Adachi, Eisuke, Koibuchi, Tomohiko, Gao, George F., Brumme, Zabrina L., Iwamoto, Aikichi
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2016
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4783116/
https://ncbi.nlm.nih.gov/pubmed/26953793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0150397
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