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Phylogenetically Older Introns Strongly Correlate With Module Boundaries in Ancient Proteins

The hypothesis that some (but not all) introns were used to construct ancient genes by exon shuffling of modules at the earliest stages of evolution is supported by the finding of an excess of phase-zero intron positions in the boundary regions of such modules in 276 ancient proteins (defined as com...

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Detalhes bibliográficos
Main Authors: Fedorov, Alexei, Roy, Scott, Cao, Xiaohong, Gilbert, Walter
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC403643/
https://ncbi.nlm.nih.gov/pubmed/12743017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.1008203
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