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Phylogenetically Older Introns Strongly Correlate With Module Boundaries in Ancient Proteins

The hypothesis that some (but not all) introns were used to construct ancient genes by exon shuffling of modules at the earliest stages of evolution is supported by the finding of an excess of phase-zero intron positions in the boundary regions of such modules in 276 ancient proteins (defined as com...

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Detaylı Bibliyografya
Yayımlandı:Genome Res
Asıl Yazarlar: Fedorov, Alexei, Roy, Scott, Cao, Xiaohong, Gilbert, Walter
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Cold Spring Harbor Laboratory Press 2003
Konular:
Online Erişim:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC403643/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12743017/
https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gr.1008203
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