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Phylogenetically Older Introns Strongly Correlate With Module Boundaries in Ancient Proteins
The hypothesis that some (but not all) introns were used to construct ancient genes by exon shuffling of modules at the earliest stages of evolution is supported by the finding of an excess of phase-zero intron positions in the boundary regions of such modules in 276 ancient proteins (defined as com...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Cold Spring Harbor Laboratory Press
2003
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC403643/ https://ncbi.nlm.nih.gov/pubmed/12743017 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.1008203 |
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