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Phylogenetically Older Introns Strongly Correlate With Module Boundaries in Ancient Proteins

The hypothesis that some (but not all) introns were used to construct ancient genes by exon shuffling of modules at the earliest stages of evolution is supported by the finding of an excess of phase-zero intron positions in the boundary regions of such modules in 276 ancient proteins (defined as com...

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Autori principali: Fedorov, Alexei, Roy, Scott, Cao, Xiaohong, Gilbert, Walter
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2003
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC403643/
https://ncbi.nlm.nih.gov/pubmed/12743017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.1008203
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