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Large-scale comparison of intron positions in mammalian genes shows intron loss but no gain

We compared intron–exon structures in 1,560 human–mouse orthologs and 360 mouse–rat orthologs. The origin of differences in intron positions between species was inferred by comparison with an outgroup, Fugu for human–mouse and human for mouse–rat. Among 10,020 intron positions in the human–mouse com...

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Main Authors: Roy, Scott W., Fedorov, Alexei, Gilbert, Walter
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2003
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC165846/
https://ncbi.nlm.nih.gov/pubmed/12777620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1232297100
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