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Large-scale comparison of intron positions in mammalian genes shows intron loss but no gain

We compared intron–exon structures in 1,560 human–mouse orthologs and 360 mouse–rat orthologs. The origin of differences in intron positions between species was inferred by comparison with an outgroup, Fugu for human–mouse and human for mouse–rat. Among 10,020 intron positions in the human–mouse com...

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Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Roy, Scott W., Fedorov, Alexei, Gilbert, Walter
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2003
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Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC165846/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12777620/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.1232297100
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