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Large-scale comparison of intron positions in mammalian genes shows intron loss but no gain

We compared intron–exon structures in 1,560 human–mouse orthologs and 360 mouse–rat orthologs. The origin of differences in intron positions between species was inferred by comparison with an outgroup, Fugu for human–mouse and human for mouse–rat. Among 10,020 intron positions in the human–mouse com...

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Bibliographic Details
Main Authors: Roy, Scott W., Fedorov, Alexei, Gilbert, Walter
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2003
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC165846/
https://ncbi.nlm.nih.gov/pubmed/12777620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1232297100
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