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Structural and Thermodynamic Characterization of Cadherin·β-Catenin·α-Catenin Complex Formation

The classical cadherin·β-catenin·α-catenin complex mediates homophilic cell-cell adhesion and mechanically couples the actin cytoskeletons of adjacent cells. Although α-catenin binds to β-catenin and to F-actin, β-catenin significantly weakens the affinity of α-catenin for F-actin. Moreover, α-caten...

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Autors principals: Pokutta, Sabine, Choi, Hee-Jung, Ahlsen, Goran, Hansen, Scott D., Weis, William I.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4036364/
https://ncbi.nlm.nih.gov/pubmed/24692547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.554709
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