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In vitro and in vivo reconstitution of the cadherin–catenin–actin complex from Caenorhabditis elegans

The ternary complex of cadherin, β-catenin, and α-catenin regulates actin-dependent cell–cell adhesion. α-Catenin can bind β-catenin and F-actin, but in mammals α-catenin either binds β-catenin as a monomer or F-actin as a homodimer. It is not known if this conformational regulation of α-catenin is...

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Hlavní autoři: Kwiatkowski, Adam V., Maiden, Stephanie L., Pokutta, Sabine, Choi, Hee-Jung, Benjamin, Jacqueline M., Lynch, Allison M., Nelson, W. James, Weis, William I., Hardin, Jeff
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2930443/
https://ncbi.nlm.nih.gov/pubmed/20689042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1007349107
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