αE-catenin regulates actin dynamics independently of cadherin-mediated cell–cell adhesion

αE-catenin binds the cell–cell adhesion complex of E-cadherin and β-catenin (β-cat) and regulates filamentous actin (F-actin) dynamics. In vitro, binding of αE-catenin to the E-cadherin–β-cat complex lowers αE-catenin affinity for F-actin, and αE-catenin alone can bind F-actin and inhibit Arp2/3 com...

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Bibliographic Details
Main Authors: Benjamin, Jacqueline M., Kwiatkowski, Adam V., Yang, Changsong, Korobova, Farida, Pokutta, Sabine, Svitkina, Tatyana, Weis, William I., Nelson, W. James
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2010
Subjects:
Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2856910/
https://ncbi.nlm.nih.gov/pubmed/20404114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200910041
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