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Structural and Thermodynamic Characterization of Cadherin·β-Catenin·α-Catenin Complex Formation
The classical cadherin·β-catenin·α-catenin complex mediates homophilic cell-cell adhesion and mechanically couples the actin cytoskeletons of adjacent cells. Although α-catenin binds to β-catenin and to F-actin, β-catenin significantly weakens the affinity of α-catenin for F-actin. Moreover, α-caten...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2014
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4036364/ https://ncbi.nlm.nih.gov/pubmed/24692547 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.554709 |
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