Molecular Mechanism of Substrate Specificity for Heparan Sulfate 2-O-Sulfotransferase

Heparan sulfate (HS) is an abundant polysaccharide in the animal kingdom with essential physiological functions. HS is composed of sulfated saccharides that are biosynthesized through a complex pathway involving multiple enzymes. In vivo regulation of this process remains unclear. HS 2-O-sulfotransf...

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Autori principali: Liu, Chunhui, Sheng, Juzheng, Krahn, Juno M., Perera, Lalith, Xu, Yongmei, Hsieh, Po-Hung, Dou, Wenfang, Liu, Jian, Pedersen, Lars C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2014
Soggetti:
Glycobiology and Extracellular Matrices
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4036349/
https://ncbi.nlm.nih.gov/pubmed/24652287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.530535
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