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Cut Site Selection by the Two Nuclease Domains of the Cas9 RNA-guided Endonuclease
Cas9, the RNA-guided DNA endonuclease from the CRISPR-Cas (clustered regularly interspaced short palindromic repeat–CRISPR-associated) system, has been adapted for genome editing and gene regulation in multiple model organisms. Here we characterize a Cas9 ortholog from Streptococcus thermophilus LMG...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Biochemistry and Molecular Biology
2014
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4036338/ https://ncbi.nlm.nih.gov/pubmed/24634220 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.539726 |
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