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N-terminal Proline-rich Domain Is Required for Scrambling Activity of Human Phospholipid Scramblases
Human phospholipid scramblase 1 (hPLSCR1), a type II integral class membrane protein, is known to mediate bidirectional scrambling of phospholipids in a Ca(2+)-dependent manner. hPLSCR2, a homolog of hPLSCR1 that lacks N-terminal proline-rich domain (PRD), did not show scramblase activity. We attrib...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4036332/ https://ncbi.nlm.nih.gov/pubmed/24648509 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.522953 |
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