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Human 60-kDa Lysophospholipase Contains an N-terminal l-Asparaginase Domain That Is Allosterically Regulated by l-Asparagine

The structural and functional characterization of human enzymes that are of potential medical and therapeutic interest is of prime significance for translational research. One of the most notable examples of a therapeutic enzyme is l-asparaginase, which has been established as an antileukemic protei...

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Autors principals: Karamitros, Christos S., Konrad, Manfred
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4036312/
https://ncbi.nlm.nih.gov/pubmed/24657844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.545038
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