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Free Glycine Accelerates the Autoproteolytic Activation of Human Asparaginase
Human asparaginase 3 (hASNase3), which belongs to the N-terminal nucleophile (Ntn) hydrolase superfamily, is synthesized as a single polypeptide that is devoid of asparaginase activity. Intramolecular autoproteolytic processing releases the amino group of Thr168, a moiety required for catalyzing asp...
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| Hlavní autoři: | , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2013
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3633088/ https://ncbi.nlm.nih.gov/pubmed/23601642 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2013.03.006 |
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