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YES, a Src Family Kinase, Is a Proximal Glucose-specific Activator of Cell Division Cycle Control Protein 42 (Cdc42) in Pancreatic Islet β Cells

Second-phase insulin secretion sustains insulin release in the face of hyperglycemia associated with insulin resistance, requiring the continued mobilization of insulin secretory granules to the plasma membrane. Cdc42, the small Rho family GTPase recognized as the proximal glucose-specific trigger t...

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Autori principali: Yoder, Stephanie M., Dineen, Stacey L., Wang, Zhanxiang, Thurmond, Debbie C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4036283/
https://ncbi.nlm.nih.gov/pubmed/24610809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.559328
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