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Activation of Cdc42 by trans interactions of the cell adhesion molecules nectins through c-Src and Cdc42-GEF FRG

Nectins, Ca(2+)-independent immunoglobulin-like cell–cell adhesion molecules, initiate cell–cell adhesion by their trans interactions and recruit cadherins to cooperatively form adherens junctions (AJs). In addition, the trans interactions of nectins induce the activation of Cdc42 and Rac small G pr...

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Detalhes bibliográficos
Main Authors: Fukuhara, Tatsuro, Shimizu, Kazuya, Kawakatsu, Tomomi, Fukuyama, Taihei, Minami, Yukiko, Honda, Tomoyuki, Hoshino, Takashi, Yamada, Tomohiro, Ogita, Hisakazu, Okada, Masato, Takai, Yoshimi
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2004
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2172271/
https://ncbi.nlm.nih.gov/pubmed/15277544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200401093
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