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Activation of Cdc42 by trans interactions of the cell adhesion molecules nectins through c-Src and Cdc42-GEF FRG

Nectins, Ca(2+)-independent immunoglobulin-like cell–cell adhesion molecules, initiate cell–cell adhesion by their trans interactions and recruit cadherins to cooperatively form adherens junctions (AJs). In addition, the trans interactions of nectins induce the activation of Cdc42 and Rac small G pr...

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Bibliografiske detaljer
Main Authors: Fukuhara, Tatsuro, Shimizu, Kazuya, Kawakatsu, Tomomi, Fukuyama, Taihei, Minami, Yukiko, Honda, Tomoyuki, Hoshino, Takashi, Yamada, Tomohiro, Ogita, Hisakazu, Okada, Masato, Takai, Yoshimi
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2004
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2172271/
https://ncbi.nlm.nih.gov/pubmed/15277544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200401093
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