Tipin Functions in the Protection against Topoisomerase I Inhibitor

The replication fork temporarily stalls when encountering an obstacle on the DNA, and replication resumes after the barrier is removed. Simultaneously, activation of the replication checkpoint delays the progression of S phase and inhibits late origin firing. Camptothecin (CPT), a topoisomerase I (T...

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Hlavní autoři: Hosono, Yoshifumi, Abe, Takuya, Higuchi, Masato, Kajii, Kosa, Sakuraba, Shuichi, Tada, Shusuke, Enomoto, Takemi, Seki, Masayuki
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2014
Témata:
DNA and Chromosomes
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4036274/
https://ncbi.nlm.nih.gov/pubmed/24573676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.531707
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