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Tipin Functions in the Protection against Topoisomerase I Inhibitor

The replication fork temporarily stalls when encountering an obstacle on the DNA, and replication resumes after the barrier is removed. Simultaneously, activation of the replication checkpoint delays the progression of S phase and inhibits late origin firing. Camptothecin (CPT), a topoisomerase I (T...

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Detalhes bibliográficos
Main Authors: Hosono, Yoshifumi, Abe, Takuya, Higuchi, Masato, Kajii, Kosa, Sakuraba, Shuichi, Tada, Shusuke, Enomoto, Takemi, Seki, Masayuki
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4036274/
https://ncbi.nlm.nih.gov/pubmed/24573676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.531707
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