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Tipin Functions in the Protection against Topoisomerase I Inhibitor
The replication fork temporarily stalls when encountering an obstacle on the DNA, and replication resumes after the barrier is removed. Simultaneously, activation of the replication checkpoint delays the progression of S phase and inhibits late origin firing. Camptothecin (CPT), a topoisomerase I (T...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2014
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4036274/ https://ncbi.nlm.nih.gov/pubmed/24573676 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.531707 |
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