Autophagy Induced by Calcium Phosphate Precipitates Targets Damaged Endosomes

Calcium phosphate precipitates (CPPs) form complexes with DNA, which enter cells via endocytosis. Under this condition CPPs induce autophagy via the canonic autophagy machinery. Here we showed that CPP-induced autophagy was also dependent on endocytosis as the process was significantly inhibited by...

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Bibliografiske detaljer
Main Authors: Chen, Xi, Khambu, Bilon, Zhang, Hao, Gao, Wentao, Li, Min, Chen, Xiaoyun, Yoshimori, Tamotsu, Yin, Xiao-Ming
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2014
Fag:
Cell Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4036255/
https://ncbi.nlm.nih.gov/pubmed/24619419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.531855
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