Autophagy Induced by Calcium Phosphate Precipitates Targets Damaged Endosomes

Calcium phosphate precipitates (CPPs) form complexes with DNA, which enter cells via endocytosis. Under this condition CPPs induce autophagy via the canonic autophagy machinery. Here we showed that CPP-induced autophagy was also dependent on endocytosis as the process was significantly inhibited by...

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Bibliographic Details
Main Authors: Chen, Xi, Khambu, Bilon, Zhang, Hao, Gao, Wentao, Li, Min, Chen, Xiaoyun, Yoshimori, Tamotsu, Yin, Xiao-Ming
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2014
Subjects:
Cell Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4036255/
https://ncbi.nlm.nih.gov/pubmed/24619419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.531855
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