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Structure-Function Analysis of Staphylococcus aureus Amidase Reveals the Determinants of Peptidoglycan Recognition and Cleavage

The bifunctional major autolysin AtlA of Staphylococcus aureus cleaves the bacterium's peptidoglycan network (PGN) at two distinct sites during cell division. Deletion of the enzyme results in large cell clusters with disordered division patterns, indicating that AtlA could be a promising targe...

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Detalhes bibliográficos
Main Authors: Büttner, Felix Michael, Zoll, Sebastian, Nega, Mulugeta, Götz, Friedrich, Stehle, Thilo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4036248/
https://ncbi.nlm.nih.gov/pubmed/24599952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.557306
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