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Structural and Enzymatic Analysis of TarM Glycosyltransferase from Staphylococcus aureus Reveals an Oligomeric Protein Specific for the Glycosylation of Wall Teichoic Acid

Anionic glycopolymers known as wall teichoic acids (WTAs) functionalize the peptidoglycan layers of many Gram-positive bacteria. WTAs play central roles in many fundamental aspects of bacterial physiology, and they are important determinants of pathogenesis and antibiotic resistance. A number of enz...

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Publicat a:J Biol Chem
Autors principals: Koç, Cengiz, Gerlach, David, Beck, Sebastian, Peschel, Andreas, Xia, Guoqing, Stehle, Thilo
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4392284/
https://ncbi.nlm.nih.gov/pubmed/25697358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.619924
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