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Methicillin resistance in Staphylococcus aureus requires glycosylated wall teichoic acids

Staphylococcus aureus peptidoglycan (PG) is densely functionalized with anionic polymers called wall teichoic acids (WTAs). These polymers contain three tailoring modifications: d-alanylation, α-O-GlcNAcylation, and β-O-GlcNAcylation. Here we describe the discovery and biochemical characterization o...

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Detalhes bibliográficos
Main Authors: Brown, Stephanie, Xia, Guoqing, Luhachack, Lyly G., Campbell, Jennifer, Meredith, Timothy C., Chen, Calvin, Winstel, Volker, Gekeler, Cordula, Irazoqui, Javier E., Peschel, Andreas, Walker, Suzanne
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3503181/
https://ncbi.nlm.nih.gov/pubmed/23027967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1209126109
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