Methicillin resistance in Staphylococcus aureus requires glycosylated wall teichoic acids

Staphylococcus aureus peptidoglycan (PG) is densely functionalized with anionic polymers called wall teichoic acids (WTAs). These polymers contain three tailoring modifications: d-alanylation, α-O-GlcNAcylation, and β-O-GlcNAcylation. Here we describe the discovery and biochemical characterization o...

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Autors principals: Brown, Stephanie, Xia, Guoqing, Luhachack, Lyly G., Campbell, Jennifer, Meredith, Timothy C., Chen, Calvin, Winstel, Volker, Gekeler, Cordula, Irazoqui, Javier E., Peschel, Andreas, Walker, Suzanne
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2012
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3503181/
https://ncbi.nlm.nih.gov/pubmed/23027967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1209126109
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