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Structural Basis of Cell Wall Cleavage by a Staphylococcal Autolysin

The major autolysins (Atl) of Staphylococcus epidermidis and S. aureus play an important role in cell separation, and their mutants are also attenuated in virulence. Therefore, autolysins represent a promising target for the development of new types of antibiotics. Here, we report the high-resolutio...

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Détails bibliographiques
Auteurs principaux: Zoll, Sebastian, Pätzold, Bernhard, Schlag, Martin, Götz, Friedrich, Kalbacher, Hubert, Stehle, Thilo
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2837410/
https://ncbi.nlm.nih.gov/pubmed/20300605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000807
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