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Ligand-Binding Properties and Conformational Dynamics of Autolysin Repeat Domains in Staphylococcal Cell Wall Recognition

The bifunctional major autolysin Atl plays a key role in staphylococcal cell separation. Processing of Atl yields catalytically active amidase (AM) and glucosaminidase (GL) domains that are each fused to repeating units. The two repeats of AM (R1 and R2) target the enzyme to the septum, where it cle...

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Detalles Bibliográficos
Main Authors: Zoll, Sebastian, Schlag, Martin, Shkumatov, Alexander V., Rautenberg, Maren, Svergun, Dmitri I., Götz, Friedrich, Stehle, Thilo
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3416534/
https://ncbi.nlm.nih.gov/pubmed/22609916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00331-12
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