Neuroplastic changes occur early in the development of pancreatic ductal adenocarcinoma

Perineural tumor invasion of intrapancreatic nerves, neurogenic inflammation, and tumor metastases along extrapancreatic nerves are key features of pancreatic malignancies. Animal studies show that chronic pancreatic inflammation produces hypertrophy and hypersensitivity of pancreatic afferents and...

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Hauptverfasser: Stopczynski, Rachelle E., Normolle, Daniel P., Hartman, Douglas J., Ying, Haoqiang, DeBerry, Jennifer J., Bielefeldt, Klaus, Rhim, Andrew D., DePinho, Ronald A., Albers, Kathryn M., Davis, Brian M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4036226/
https://ncbi.nlm.nih.gov/pubmed/24448244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-13-2050
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