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Neuroplastic changes occur early in the development of pancreatic ductal adenocarcinoma

Perineural tumor invasion of intrapancreatic nerves, neurogenic inflammation, and tumor metastases along extrapancreatic nerves are key features of pancreatic malignancies. Animal studies show that chronic pancreatic inflammation produces hypertrophy and hypersensitivity of pancreatic afferents and...

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Detalhes bibliográficos
Main Authors: Stopczynski, Rachelle E., Normolle, Daniel P., Hartman, Douglas J., Ying, Haoqiang, DeBerry, Jennifer J., Bielefeldt, Klaus, Rhim, Andrew D., DePinho, Ronald A., Albers, Kathryn M., Davis, Brian M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4036226/
https://ncbi.nlm.nih.gov/pubmed/24448244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-13-2050
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