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Conserved Residues in the N Terminus of Lipin-1 Are Required for Binding to Protein Phosphatase-1c, Nuclear Translocation, and Phosphatidate Phosphatase Activity

Lipin-1 is a phosphatidate phosphatase in glycerolipid biosynthesis and signal transduction. It also serves as a transcriptional co-regulator to control lipid metabolism and adipogenesis. These functions are controlled partly by its subcellular distribution. Hyperphosphorylated lipin-1 remains seque...

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Bibliografski detalji
Glavni autori: Kok, Bernard P. C., Skene-Arnold, Tamara D., Ling, Ji, Benesch, Matthew G. K., Dewald, Jay, Harris, Thurl E., Holmes, Charles F. B., Brindley, David N.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2014
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4036199/
https://ncbi.nlm.nih.gov/pubmed/24558042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.552612
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