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Thematic Review Series: Glycerolipids. Multiple roles for lipins/phosphatidate phosphatase enzymes in lipid metabolism

Phosphatidate phosphatase-1 (PAP1) enzymes have a key role in glycerolipid synthesis through the conversion of phosphatidate to diacylglycerol, the immediate precursor of triacylglycerol, phosphatidylcholine, and phosphatidylethanolamine. PAP1 activity in mammals is determined by the lipin family of...

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Detalles Bibliográficos
Main Authors: Reue, Karen, Brindley, David N.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2008
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2582367/
https://ncbi.nlm.nih.gov/pubmed/18791037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.R800019-JLR200
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